1,3,5-Triazin-2(1H)-one, 4-amino-1-(2,3,5-tri-O-acetyl-b-D-ribofuranosyl)-
2',3',5'-Triacetyl -azacytidine
CAS: 10302-78-0
Molecular Formula: C14H18N4O8
1,3,5-Triazin-2(1H)-one, 4-amino-1-(2,3,5-tri-O-acetyl-b-D-ribofuranosyl)- - Names and Identifiers
| Name | 2',3',5'-Triacetyl -azacytidine |
| Synonyms | Nsc291930 Intermediate of Azacitidine 2',3',5'-Triacetyl -azacytidine 2',3',5'-triacetyl-5-Azacytidine 2',3',5'-triacetyl-5-Azacytosine 2'',3'',5''-Triacetyl -Azacytidine 2'',3'',5''-Triacetyl -azacytidine 4-amino-1-(2,3,5-tri-O-acetylpentofuranosyl)-1,3,5-triazin-2(1H)-one 1,3,5-Triazin-2(1H)-one, 4-amino-1-(2,3,5-tri-O-acetyl-b-D-ribofuranosyl)- S-Triazin-2(1H)-one, 4-amino-1-.beta.-D-ribofuranosyl-, triacetate (ester) 1,3,5-Triazin-2(1H)-one, 4-aMino-1-(2,3,5-tri-O-acetyl-b-D-ribofuranosyl)- 1,3,5-Triazin-2(1H)-one, 4-amino-1-(2,3,5-tri-o-acetyl-.beta.-D-ribofuranosyl)- (2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(4-amino-2-oxo-1,3,5-triazin-1(2H)-yl)tetrahydrofuran-3,4-diyl diacetate |
| CAS | 10302-78-0 |
| InChI | InChI=1/C14H18N4O8/c1-6(19)23-4-9-10(24-7(2)20)11(25-8(3)21)12(26-9)18-5-16-13(15)17-14(18)22/h5,9-12H,4H2,1-3H3,(H2,15,17,22) |
1,3,5-Triazin-2(1H)-one, 4-amino-1-(2,3,5-tri-O-acetyl-b-D-ribofuranosyl)- - Physico-chemical Properties
| Molecular Formula | C14H18N4O8 |
| Molar Mass | 370.31 |
| Density | 1.60±0.1 g/cm3(Predicted) |
| Boling Point | 497.3±55.0 °C(Predicted) |
| Flash Point | 254.6°C |
| Vapor Presure | 5E-10mmHg at 25°C |
| pKa | 3.06±0.20(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,2-8°C |
| Refractive Index | 1.633 |
| Physical and Chemical Properties | Storage Conditions: Store at 0-5 ℃ |
1,3,5-Triazin-2(1H)-one, 4-amino-1-(2,3,5-tri-O-acetyl-b-D-ribofuranosyl)- - Introduction
Triacetyl -5-, also known as 3-acetylamino-5-aza-1-Δ4-piperidinone nucleoside (azacytidine nucleoside), is a nucleoside compound. The following is a description of its nature, use, formulation and safety information:
Nature:
Triacetyl-5-azacytidine is a white crystalline solid that is stable at ambient temperature. It has a strong polarity, soluble in water and organic solvents. Its chemical structure contains nitrogen and amide functional groups, which make it have special chemical and biological activities.
Use:
Triacetyl -5-azacytidine is mainly used as a pharmaceutical intermediate and research reagent. In the field of medicine, it is used to synthesize antiviral drugs, such as anti-HIV drugs. In the field of scientific research, it is often used to synthesize biologically active molecules or heterocyclic compounds. In addition, it can also be used for DNA synthesis and virus suppression.
Preparation Method:
Triacetyl -5-azacytidine is generally obtained by chemical synthesis. Common methods of preparation include synthesis of nucleotides and chemical modification of functional groups. The specific preparation method can be selected according to the desired purity and scale.
Safety Information:
Triacetyl-5-azacytidine is less toxic and dangerous, but it is still a chemical substance that needs to be handled correctly in the laboratory. When handling, take appropriate protective measures, such as wearing gloves and protective glasses, to avoid inhalation or contact with the skin. If ingested by mistake or into the eyes or skin, rinse immediately with plenty of water and seek medical help. In addition, the compound should be stored in a dry, cool, well-ventilated place, away from fire sources and flammable materials. During use and storage, be sure to carefully read and follow the relevant safety data sheets and instructions for use.
Nature:
Triacetyl-5-azacytidine is a white crystalline solid that is stable at ambient temperature. It has a strong polarity, soluble in water and organic solvents. Its chemical structure contains nitrogen and amide functional groups, which make it have special chemical and biological activities.
Use:
Triacetyl -5-azacytidine is mainly used as a pharmaceutical intermediate and research reagent. In the field of medicine, it is used to synthesize antiviral drugs, such as anti-HIV drugs. In the field of scientific research, it is often used to synthesize biologically active molecules or heterocyclic compounds. In addition, it can also be used for DNA synthesis and virus suppression.
Preparation Method:
Triacetyl -5-azacytidine is generally obtained by chemical synthesis. Common methods of preparation include synthesis of nucleotides and chemical modification of functional groups. The specific preparation method can be selected according to the desired purity and scale.
Safety Information:
Triacetyl-5-azacytidine is less toxic and dangerous, but it is still a chemical substance that needs to be handled correctly in the laboratory. When handling, take appropriate protective measures, such as wearing gloves and protective glasses, to avoid inhalation or contact with the skin. If ingested by mistake or into the eyes or skin, rinse immediately with plenty of water and seek medical help. In addition, the compound should be stored in a dry, cool, well-ventilated place, away from fire sources and flammable materials. During use and storage, be sure to carefully read and follow the relevant safety data sheets and instructions for use.
Last Update：2024-04-09 20:52:54
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Product Name: Azacitidine Impurity 48 Visit Supplier Webpage Request for quotationCAS: 10302-78-0
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Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Product Name: 2'',3'',5''-Triacetyl -azacytidine Visit Supplier Webpage Request for quotation
CAS: 10302-78-0
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Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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CAS: 10302-78-0
Tel: 18301782025
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QQ: 3008007409
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View History
1,3,5-Triazin-2(1H)-one, 4-amino-1-(2,3,5-tri-O-acetyl-b-D-ribofuranosyl)-
氨基甲烷溶液
3-Benzoyl Acrylic Acid Ethyl Ester
乙基3-外双环氨基[2.2.1]庚烷-2-内羧酸盐酸盐
n-1-naphthalenyl-acetamid
5-氯苯基溴化镁
氨基甲烷溶液
3-Benzoyl Acrylic Acid Ethyl Ester
乙基3-外双环氨基[2.2.1]庚烷-2-内羧酸盐酸盐
n-1-naphthalenyl-acetamid
5-氯苯基溴化镁